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Antioxidant and cytotoxic activity of Tecoma stans against lung cancer cell line (A549) BJPS
Robinson,Jayachandran Philip; Suriya,Kumaresan; Subbaiya,Ramasamy; Ponmurugan,Ponnusamy.
ABSTRACT Human have been constantly using plants and plant products to overcome many diseases. The antioxidant property of the plant sources is studied to obtain an efficacious drug against cancer. The objectives of the present study is to evaluate the antioxidant and cytotoxic activity of the Tecoma stans extracts against lung cancer cell line in comparison with vincristine drug. The antioxidant activity was studied using the standard DPPH assay and the cytotoxic activity using MTT assay. DPPH assay results show that methanolic extract of T. stans in higher concentration show better antioxidant potential than the standard L-ascorbic acid. They exhibited strong antioxidant potential at 20 µg/mL concentration. The absorbance at 517 nm showed that in the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tecoma stans/extract/cytotoxicity; Tecoma stans/extract/antioxidant activity; Free radical scavenging; Plant extracts; Lung cancer cell line/study/drugs.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000300605
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